Intestinal absorption of essential fatty acids under physiological and essential fatty acid-deficient conditions

Intestinal absorption of essential fatty acids under physiological and essential fatty acid-deficient conditions.

The adequate supply of essential fatty acids (EFA) to the body depends upon sufficient dietary intake and subsequent efficient intestinal absorption. Lipid malabsorption is not only a leading cause of EFA deficiency (EFAD), but also occurs secondarily to EFAD. Understanding the relationship between EFAD and lipid malabsorption may be helpful in the development and optimization of oral treatment...

Fat Absorption in Essential Fatty Acid Deficiency*

The various gross symptoms of essential fatty acid deficiency in the rat are well recognized, but little is known about the metabolic features of this disease. The purpose of this investigation was to study the influence of fat deficiency on the rate of absorption and transport of fat through the intestinal mucosa. The scheme of fat labeling by the use of spectroscopically active methyl esters ...

Essential fatty acids and inflammation.

Consequences of Essential Fatty Acids

Essential fatty acids (EFA) are nutrients that form an amazingly large array of bioactive mediators that act on a large family of selective receptors. Nearly every cell and tissue in the human body expresses at least one of these receptors, allowing EFA-based signaling to influence nearly every aspect of human physiology. In this way, the health consequences of specific gene-environment interac...

Metabolism of Essential Fatty Acids

The fat deficiency disease in the rat (I), dog (2), and chick (3) is characterized in part by sharply increased concentrations of one or more trienoic acids in the tissues, as indicated by alkali isomerization analyses. Indeed, the increase in conjugatable triene in the mitochondrial fatty acids may be the first noticeable symptom of the onset of fat deficiency (4). The major triene component o...